When a lymph node becomes abnormally large and firm, especially in the setting of a known or suspected cancer, it may indicate metastasis – the spread of cancer cells from a primary site to other parts of the body. One of the most effective ways to confirm this is through a biopsy of the enlarged lymph node.
A large metastatic lymph node biopsy is a crucial diagnostic procedure. It involves removing a sample of tissue from the affected lymph node to examine it under a microscope. This helps to determine if cancer cells are present, what type they are, and how aggressive the disease might be. The procedure may be done through a fine needle aspiration, core needle biopsy, or an excisional biopsy, depending on the location and size of the node.
Dr. Arindam Mandal, a respected name in surgical oncology, often performs such biopsies as part of a broader cancer diagnosis and staging process. According to Dr. Mandal, early and accurate diagnosis is critical in planning the right treatment, whether it involves surgery, chemotherapy, radiation, or a combination.
Metastatic nodes are often found in cancers such as breast, head and neck, lung, and gastrointestinal malignancies. Identifying them early allows oncologists to tailor therapy more effectively and potentially improve outcomes.
Patients may experience mild discomfort or swelling after the biopsy, but complications are rare. Dr. Mandal emphasizes the importance of follow-up and timely treatment decisions after the biopsy results are available.
With advancements in imaging and minimally invasive techniques, lymph node biopsies today are safer and more precise than ever, playing a key role in the journey toward recovery.
